Cloxacillin (Cloxacillin)
Overview of Cloxacillin
Cloxacillin is an isoxazolyl penicillin. Penicillin is derived directly or indirectly from strains of fungi of the genus Penicillium and other soil inhabiting fungi grown on special culture media. The structure of penicillin consists of a thiazolidine ring connected to a ß lactam ring, which is attached to a side chain. its use is limited to treatment of penicillinase-producing Staphylococcus aureus infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Cloxacillin (Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.
Indication of Cloxacillin
Cloxacillin is primarily indicated in conditions like Bacterial infections, Bone and joint infection, Cystitis, Endocarditis, Enterocolitis, Meningitis associated with spina bifida, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections.
Contraindication of Cloxacillin
Cloxacillin is contraindicated in conditions like Hypersensitivity.
Side Effects of Cloxacillin
The severe or irreversible adverse effects of Cloxacillin, which give rise to further complications include Cholestatic jaundice, Hemolytic anemia, Blood dyscrasias, Seizures, Interstitial nephritis, Cholestasis, Neurotoxicity.,Cloxacillin produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis. which are responsible for the discontinuation of Cloxacillin therapy.,The signs and symptoms that are produced after the acute overdosage of Cloxacillin include Vomiting, Diarrhea, GI disturbances, Abdominal discomfort.,The symptomatic adverse reactions produced by Cloxacillin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Rashes, Phlebitis, Glossitis, StomatitisX, Nausea and vomiting, GI disturbance, Hyperthermia.
Precautions of Cloxacillin
Cloxacillin should be used with caution in patients with any other illnesses or any allergy especially to penicillin or other antibiotics.This medication should be used only if clearly needed during pregnancy or lactation.