Atosiban (Atosiban)
Overview of Atosiban
Atosiban is a peptide analogue of oxytocin but with oxytocin properties. It has been investigated by IV-inf as a tocolytic in the management of premature labor, but there is some concern about adverse effects on the fetus.
Indication of Atosiban
Atosiban is primarily indicated in conditions like Prostate cancer, flare with initial gonadorelin therapy, Uncomplicated premature labor.
Contraindication of Atosiban
Atosiban is contraindicated in conditions like Eclampsia,Intrauterine fetal death,Antepartum haemorrhage,Nausea and vomiting of terminal illness,Motor TICS and adjunctive treatment in chorea,Autoimmune conditions,Dermatological conditions caused or aggravated by sunlight,Placenta previa.
Side Effects of Atosiban
The symptomatic adverse reactions produced by Atosiban are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Vomiting, Fever, Tachycardia, Insomnia, Rashes, Hot flushes, Hyperglycemia, Injection site reactions.
Precautions of Atosiban
Monitor blood loss after delivery;Intra-uterine growth retardation; hepatic impairment ,renal impairment