Clorazepate k (Clorazepate k)
Overview of Clorazepate k
Clorazepate (K) is a benzodiazipine. Benzodiazipines are the most widely used anxiolytic drugs. The benzodiazipines are more effective and safer. They have largely replaced barbiturates and meprobamate in the treatment of anxiety. Clorazepate is administered orally and is also given in seizure disorders.
Indication of Clorazepate k
Clorazepate K is primarily indicated in conditions like Alcohol withdrawal, Anxiety, Insomnia, Neurosis, Partial seizures, Premedication in anaesthesia, Psychoneurosis, Psychosomatic disorders, Suppression of transplant rejection, and can also be given in adjunctive therapy as an alternative drug of choice in Epilepsy.
Contraindication of Clorazepate k
Clorazepate (K) is contraindicated in conditions like Pulmonary insufficiency,Narrow-angle glaucoma,Hypersensitivity.
Side Effects of Clorazepate k
The severe or irreversible adverse effects of Clorazepate (K), which give rise to further complications include Aggression, Jaundice, Dependence, Psychological impairment, Cerebral atrophy.,Clorazepate (K) produces potentially life-threatening effects which include Blood dyscrasias. which are responsible for the discontinuation of Clorazepate (K) therapy.,The signs and symptoms that are produced after the acute overdosage of Clorazepate (K) include Coma, Drowsiness, Respiratory depression, Ataxia, Nystagmus, Mental confusion.,The symptomatic adverse reactions produced by Clorazepate (K) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Drowsiness, Irritability, Ataxia, Skin rashes, Dry mouth, Blurred vision, Confusion, GI upset, Tremor, Diplopia, Nightmares, Paradoxical rage, Slurred speech, Syncope, Euphoria, Xerostomia.
Precautions of Clorazepate k
Perform periodic blood counts and liver function tests during long term therapy. Clorazepate potassium should be used with caution in patients if increased salivation cause respiratory difficulty, because it may produce an increase in salivation. Give least amount of drug to patients in whom depression accompanies anxiety and suicidal tendencies may be present. It should be used with caution (if it contain tartrazine) in patients with aspirin hypersensitivity because it may cause allergic reaction (including bronchial asthma).