Orlistat (Orlistat)
Overview of Orlistat
Orlistat is a peptic and pancreatic lipase inhibitor that reduces the absorption of fat. Orlistat is used as an adjunct in the treatment of obesity, in those individuals who have a high intake of fats or in the presence of risk factors such as type II diabetes, hypertension and hypercholesterolemia.
Indication of Orlistat
Orlistat is primarily indicated in conditions like Obesity.
Contraindication of Orlistat
Orlistat is contraindicated in conditions like Cholestasis,Pregnancy,Breast feeding,Controlled hypotension in anaesthesia.
Side Effects of Orlistat
The symptomatic adverse reactions produced by Orlistat are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Headache, Fatigue, Anxiety, Abdominal pain, Hypersensitivity reactions, Menstrual irregularity, Fecal incontinence, Liquid oily stools, Rectal pain, Faecal urgency.
Precautions of Orlistat
Orlistat should be used with caution in patients with diabetes mellitus. It may impair absorption of fat-soluble vitamins. MULTIVITAMINS: If a multivitamin suppliment is required, it should be taken atleast two hours after orlistat dose or at bedtime.