Galantamine (Galantamine)
Overview of Galantamine
Galantamine is a reversible inhibitor of cholinestrase activity and it also has nicotinic receptor agonist properties. The actions and general properties similar to neostigmine. Galantamine is used in the treatment of mild to moderate dementia in Alzheimer`s disease and in various neuromuscular disorders.
Indication of Galantamine
Galantamine is primarily indicated in conditions like Mild to moderate dementia in alzheimer's disease, and can also be given in adjunctive therapy as an alternative drug of choice in Muscle relaxation.
Contraindication of Galantamine
Galantamine is contraindicated in conditions like Breast feeding,Adjunct in treatment of opioid dependance.
Side Effects of Galantamine
The symptomatic adverse reactions produced by Galantamine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Fatigue, Anorexia, Diarrhea, Tremors, Abdominal pain, Bradycardia, Weight LossX, Dyspepsia, Nausea and vomiting, Muscle cramps, UTI, Hypertension, dyspepsia.
Precautions of Galantamine
Galantamine should be used with caution in patients with hepatic impairment (avoid if severe); sick sinus syndrome or other supraventricular conduction abnormalities; susceptibility to peptic ulcer; asthma, chronic obstructive pulmonary disease; may exacerbate extrapyramidal symptoms; hepatic impairment.