Clavulanic Acid (Clavulanic Acid)
Overview of Clavulanic Acid
Clavulanic Acid is a ß lactamase inhibitor. Clavulanic Acid is structurally related to the penicillins and used in combination with penicillin antibiotic to treat variety of bacterial infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Clavulanic Acid is important to take the drug for the full time period as prescribed. If you discontinue the therapy it may result in ineffective treatment.
Indication of Clavulanic Acid
Clavulanic Acid is primarily indicated in conditions like Bacterial infections, Myeloablative therapy followed by bone marrow transplantation, Respiratory tract infections, Urinary tract infection.
Contraindication of Clavulanic Acid
Clavulanic Acid is contraindicated in conditions like Glandular fever,Penicillin hypersensitivity.
Side Effects of Clavulanic Acid
The severe or irreversible adverse effects of Clavulanic Acid, which give rise to further complications include Hypersensitivity reactions, Eosinophilia, Severe diarrhea, Hepatic cholestasis.,Clavulanic Acid produces potentially life-threatening effects which include Pseudomembranous colitis, Anaphylaxis. which are responsible for the discontinuation of Clavulanic Acid therapy.,The signs and symptoms that are produced after the acute overdosage of Clavulanic Acid include Nausea, Vomiting.,The symptomatic adverse reactions produced by Clavulanic Acid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Fever, Maculopapular rash, Urticaria, Increase in serum transaminase.
Precautions of Clavulanic Acid
Clavulanic acid should be used with caution in patients with other illnesses or any allergy especially to penicillin or other antibiotics. This medication should be used only if clearly needed during pregnancy or lactation.