Terlipressin (Terlipressin)
Overview of Terlipressin
A vasopressin analogue, which is used to control bleeding from esophageal varices . It is administered intravenously.
Indication of Terlipressin
Terlipressin is primarily indicated in conditions like Bleeding from oesophageal varices, Bleeding oesophageal varices.
Contraindication of Terlipressin
Terlipressin is contraindicated in conditions like Vascular disease.
Side Effects of Terlipressin
The severe or irreversible adverse effects of Terlipressin, which give rise to further complications include Cardiac arrhythmias, Angina, Abdominal cramps.,Terlipressin produces potentially life-threatening effects which include Bradycardia, Myocardial infarction, Cardiac failure. which are responsible for the discontinuation of Terlipressin therapy.,The signs and symptoms that are produced after the acute overdosage of Terlipressin include Hypertension, Increase in BP, Water retention.,The symptomatic adverse reactions produced by Terlipressin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Abdominal cramps, Weakness of the leg, Skin pallor.
Precautions of Terlipressin
Avoid use in patients with chronic nephritis with nitrogen retension. Use with caution and in small doses in patients with vascular disease, especially of coronary arteries. It should be given with care to patients with asthma, migrane, epilepsy, heart failure or hypertension. Fluid retension should be adjusted to avoid hyponatraemia.