Calcium-Glubionate (Calcium-Glubionate)
Overview of Calcium-Glubionate
Calcium Glubionate is used in the management of hypocalcaemia and calcium deficiency states resulting from dietry deficiency or aging (e.g Osteoprosis), in combination with other calcium salts.
Indication of Calcium-Glubionate
Calcium Glubionate is primarily indicated in conditions like Cardiopulmonary resuscitation, Hypocalcaemia, Osteoporosis prophylaxis, and can also be given in adjunctive therapy as an alternative drug of choice in Severe hyperkalaemia, Severe hypermagnesaemia.
Contraindication of Calcium-Glubionate
Calcium Glubionate is contraindicated in conditions like Hypercalcaemia,Renal calculi.
Side Effects of Calcium-Glubionate
The severe or irreversible adverse effects of Calcium Glubionate, which give rise to further complications include Cardiac arrhythmias, Renal calculi, Sinus bradycardia.,Calcium Glubionate produces potentially life-threatening effects which include Coma, Cardiac Arrest. which are responsible for the discontinuation of Calcium Glubionate therapy.,The signs and symptoms that are produced after the acute overdosage of Calcium Glubionate include Hypercalcemia.,The symptomatic adverse reactions produced by Calcium Glubionate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Anorexia, Constipation, Abdominal pain, Syncope, GI irritation, Mental disturbances.
Precautions of Calcium-Glubionate
Solution of calcium salts are irritant and care should be taken to prevent extravasation during intravenous injection. Calcium glubionate should be used with caution in patients with impaired renal function, pre-existing cardiac arrhythmias, diarrhoea, malabsorption or diseases associated with elevated vitamin D concentrations such as sarcoidosis. Generally calcium salts should be avoided in patients with calcium renal calculi. Plasma-calcium concentrations should be monitored closely in patients with renal insufficiency and during parentral administration and if large doses of vitamin D are used.