Ritonavir (Ritonavir)
Overview of Ritonavir
Ritonavir is an antiretroviral agent belongs to the group of known as protease inhibitors, but ritonavir has improved oral bioavailability compared with other protease inhibitors. Ritonavir is used either alone, or in combination with nucleoside reverse transcriptase inhibitor, for the treatment of progressive or advanced HIV infection.
Indication of Ritonavir
Ritonavir is primarily indicated in conditions like Chronic lymphocytic leukaemia, HIV infection, Schizophrenia and other psychoses.
Contraindication of Ritonavir
No data regarding the contra indications of Ritonavir is available.
Side Effects of Ritonavir
The severe or irreversible adverse effects of Ritonavir, which give rise to further complications include Orthostatic hypotension, Vasodilation, Syncope, Myalgia, Renal insufficiency.,The symptomatic adverse reactions produced by Ritonavir are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Diarrhea, Pruritus, Skin RashX, Taste disturbance, Asthenia, Nausea and vomiting.
Precautions of Ritonavir
Caution is required in diabetic patient, patients with hemophilia who may experienced increased bleeding. It should be used with caution and possible dose reduction is needed in hepatic impairment. Adequate hydration is recommended to avoid any risk of nephrolithiasis. Monotoring is required in case of renal impairment.