Interferon Beta (Interferon Beta)
Overview of Interferon Beta
Interferons are potent cytokines that possess antiviral, immunomodulating and antiproliferative actions. The interferones bind to specific cell-surface receptors that initiate a series of intracellular events, induction of certain enzymes, inhibition of cell-proliferation, and enhancement of immune activities. It (IFNB) is a type of interferon produced by fibroblasts and epithelial cells. The term "it" used here encompasses products that are further differentiated as either it-1a or it-1b. it-I a, a 166-amino acid recombinant glycoprotein, and it-I b, a 165-amino acid recombinant protein, used in the treatment of multiple sclerosisto reduce the frequency of clinical exacerbations.
Indication of Interferon Beta
Interferon Beta is primarily indicated in conditions like Condyloma acuminata, Hairy cell leukaemia, Hepatitis B, Hepatitis C, Herpes simplex infections, Multiple sclerosis.
Contraindication of Interferon Beta
Interferon Beta is contraindicated in conditions like Depression,Lactation.
Side Effects of Interferon Beta
The severe or irreversible adverse effects of Interferon Beta, which give rise to further complications include Sinus tachycardia, Neutropenia, Hypothyroidism, Depression, Pancytopenia, Hyperthyroidism.,The signs and symptoms that are produced after the acute overdosage of Interferon Beta include Anemia, Depression, Neutropenia, Hyperthyroidism.,The symptomatic adverse reactions produced by Interferon Beta are more or less tolerable and if they become severe, they can be treated symptomatically, these include Alopecia, Anorexia, Fever, Skin reactions, Confusion, Malaise, Arthralgia, Swelling, Anemia, Muscle aching, Leukopenia, Skin redness, Lymphopenia, Confusion, Alopecia.
Precautions of Interferon Beta
It should be used with caution in patients with any pre-existing liver, kidney, heart or thyroid disease, blood disorders, history of depression or other mental condition, lung disease, diabetes, seizures, brain tumor, multiple sclerosis, lupus, sarcoidosis or any drug allergy. It should be used with caution when engaging in activities requiring alertness. Limit alcohol intake. It should be used only when clearly needed during pregnancy.