Chloral Hydrate (Chloral Hydrate)
Overview of Chloral Hydrate
Chloral Hydrate is a trichlorinated derivative of acetaldehyde that is converted to trichloroethanol in the body. A hypnotic and is used as a sleeping aid to improve sleep disturbances. It has also been used in the treatment of eclampsia and tetanus.
Indication of Chloral Hydrate
Chloral Hydrate is primarily indicated in conditions like Insomnia, Postoperative sedation, Pre-operative sedation, and can also be given in adjunctive therapy as an alternative drug of choice in Nausea, vertigo, labyrinthine disorders.
Contraindication of Chloral Hydrate
Chloral Hydrate is contraindicated in conditions like Renal failure,Gastritis,Hepatic failure,Porphyria,Cardiac disease.
Side Effects of Chloral Hydrate
The severe or irreversible adverse effects of Chloral Hydrate, which give rise to further complications include Bradycardia, Eosinophilia, Eosinophilia, Liver cirrhosis, CNS depression, Hypoprothorombinemia, Hepatic encephalopathy exacerbation.,Chloral Hydrate produces potentially life-threatening effects which include Hepatic coma, Drowsiness, Semicoma. which are responsible for the discontinuation of Chloral Hydrate therapy.,The signs and symptoms that are produced after the acute overdosage of Chloral Hydrate include Cardiac arrhythmias, Convulsions, Jaundice, Respiratory depression, Respiratory depression, Jaundice, Slurred speech, Respiratory depression.,The symptomatic adverse reactions produced by Chloral Hydrate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Ataxia, Confusion, Pain, Skin RashX, Hallucination, Gastric irritation, Hypersensitivity, Disorientation, Nightmares, Confusion, Ataxia.
Precautions of Chloral Hydrate
Patients should observe caution while driving or performing other tasks requiring alertness, because it may cause drowsiness. Do not use chloral hydrate in larger doses in patients with severe cardiac disease. Exercise caution in administering to patients prone to addiction. It should be used with caution (if contains tartrazine) in patients with aspirin hypersensitivity, because may produced allergic reaction (including bronchial asthma).