Bicalutamide (Bicalutamide)
Overview of Bicalutamide
Bicalutamide is an anti-androgen, used for prostate cancer either alone or as an adjunct to other therapy, according to the clinical circumstances. It inhibits the tumour "flare"which may occur after commencing gonadorelin analogue (e.g diethylstilbestrol) administration.
Indication of Bicalutamide
Bicalutamide is primarily indicated in conditions like Prostatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Prostate cancer.
Contraindication of Bicalutamide
Bicalutamide is contraindicated in conditions like Hypersensitivity.
Side Effects of Bicalutamide
The severe or irreversible adverse effects of Bicalutamide, which give rise to further complications include Congestive heart failure, Angina.,The symptomatic adverse reactions produced by Bicalutamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Tiredness, Fatigue, Nausea, Vomiting, Anorexia, Diarrhea, Fever, Anxiety, Nervousness, Chills, Rashes, Confusion, Dyspepsia, Depression, Weight gain, Somnolence, Cough, Hot flushes, Xerostomia.
Precautions of Bicalutamide
Bicalutamide should be used with caution in patients with moderate to severe hepatic impairment. Avoid use in females and childrens.