Theobromine (Theobromine)
Overview of Theobromine
Theobromine is alkaloid prepared from the dried ripe seed of Theobroma cacao or made synthetically from xanthine. It has physiologic properties similar to those of caffeine. its major source is beverages (tea, cocoa and coffee). Chemically Theobromine is 3, 7-dimethylxanthine. It can be employed as a diuretic, it acts by inhibiting reabsorption of sodium and chloride in the renal tubules. Theobromine is less toxic, and thus can be employed on occasions when the more toxic diuretics are contraindicated such as when renal function is poor. The wide choice of more effective diuretics has limited the use of it as a diuretic. It dilates the coronary arteries and increase the coronary blood flow.
Indication of Theobromine
Indications
Contraindication of Theobromine
Theobromine is contraindicated in conditions like Hypersensitivity.
Side Effects of Theobromine
The symptomatic adverse reactions produced by Theobromine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Anxiety, Restlessness, Tremors, Sleeplessness, Nausea and vomiting, Loss of appetite.
Precautions of Theobromine
Theobromine should be used with caution in patients with severe cardiac, kidney or liver disease, hyperthyroidism, congestive heart failure (CHF), peptic ulcer. It should be used with caution in neonates and elderly persons.