Cefixime (Cefixime)
Overview of Cefixime
Cefixime is a third generation semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7-aminocephalosporic acid and are closely related to penicillins in structure. Cephalosporins have a six membered sulfur containing ring adjoining a ß lactam ring. Cefixime is effective in a large variety of bacterial infections, such as respiratory tract, ear, skin, gonorrhea, otitis media, and urinary tract infections. Administered orally. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. Cefixime is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment.
Indication of Cefixime
Cefixime is primarily indicated in conditions like Bronchitis, Cardiopulmonary resuscitation, Gonorrhoea, Otitis media, Pharyngitis, Pneumonia, Respiratory tract infections, Uncomplicated UTIs, and can also be given in adjunctive therapy as an alternative drug of choice in Gonococcal urethritis, Typhoid.
Contraindication of Cefixime
Cefixime is contraindicated in conditions like Hypersensitivity.
Side Effects of Cefixime
The severe or irreversible adverse effects of Cefixime, which give rise to further complications include Pseudomembranous colitis, Thrombocytopenia, Thrombophlebitis, Leucopenia, Seizures, Vaginitis.,The symptomatic adverse reactions produced by Cefixime are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Nausea, Vomiting, Anorexia, Diarrhea, Abdominal pain, Urticaria, Pruritus, Dyspepsia, Hypersensitivity, Increased intracranial pressure, Xerostomia, Pain at injection site.
Precautions of Cefixime
Persons allergic to penicillin-type antibiotics should use this medication with caution. An allergy may exist to this as well. This drug should be used only if clearly needed during pregnancy or lactation. Cefixime should be discontinued if diarrhea is severe.